Effects of Nano Zinc Oxide on the Hind Limb Bud of NMRI mouse embryos

Document Type: Original Article


Nanomaterials are particles with 10 to100 nanometer size. They can easily be transported
through the skin, lung alveoli, and placenta. Materials in nano scales show different properties
compared with the same materials in macro or larger scale. It is found that zinc element is an
essential metal for normal physiological functions. However increase or decrease of this element
during pregnancy, for example with using cosmetics and deodorants, can be teratogen and cause
several fetal abnormalities. Given this fact, this study was conducted to investigate the effects of
nano zinc oxide on the developmental stages of hind limb budsin NMRI mice embryos