Insights into the autistic disorder and potential therapeutic approaches

Document Type: Original Article


Autism and autism spectrum disorders (ASDs) such as Rett syndrome and Asperger syndrome
are enigmatic and complex neurodevelopmental disorders, thought to have originated in
particular interactions of genetic and environmental factors. Despite the extensive research,
exact mechanism of pathogenesis is not still completely understood. ASDs are characterized
by deficits and abnormalities in communication and social interactions, besides repetitive and
stereotypic verbal/nonverbal behaviors. There are no effective drugs for the treatment of these
conditions and as the frequency of ASDs in the children has risen over the last decade, further
studies will be needed to better address the treatment. In this brief review we discuss the etiology
of autism and possible novel approaches for its management in the near future